Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis
Smith BN., Topp SD., Fallini C., Shibata H., Chen H-J., Troakes C., King A., Ticozzi N., Kenna KP., Soragia-Gkazi A., Miller JW., Sato A., Dias DM., Jeon M., Vance C., Wong CH., de Majo M., Kattuah W., Mitchell JC., Scotter EL., Parkin NW., Sapp PC., Nolan M., Nestor PJ., Simpson M., Weale M., Lek M., Baas F., Vianney de Jong JM., ten Asbroek ALMA., Redondo AG., Esteban-Pérez J., Tiloca C., Verde F., Duga S., Leigh N., Pall H., Morrison KE., Al-Chalabi A., Shaw PJ., Kirby J., Turner MR., Talbot K., Hardiman O., Glass JD., De Belleroche J., Maki M., Moss SE., Miller C., Gellera C., Ratti A., Al-Sarraj S., Brown RH., Silani V., Landers JE., Shaw CE.
Annexin A11 mutations, implicated in ALS, prevent binding to calcyclin and induce the formation of cytoplasmic inclusions.