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Search results (205)

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Dopamine release from Parkinson’s patient-derived neurons is disrupted due to impaired synaptic vesicle loading

Cramb KML. et al, (2026)

SARM1 activation induces reversible mitochondrial dysfunction and can be prevented in human neurons by antisense oligonucleotides

Loreto A. et al, (2025), Neurobiology of Disease, 213, 106986 - 106986

Recent developments in gene therapy for Parkinson’s disease

Szunyogh S. et al, (2025), Molecular Therapy, 33, 2052 - 2064

Tau depletion in human neurons mitigates Aβ-driven toxicity.

Ng B. et al, (2024), Molecular psychiatry, 29, 2009 - 2020

Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation

Do QB. et al, (2024), npj Parkinson's Disease, 10

Single-cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging, and disease

Kilfeather P. et al, (2024), Cell Reports, 43, 113784 - 113784

Inhibition of striatal dopamine release by the L‐type calcium channel inhibitor isradipine co‐varies with risk factors for Parkinson's

Brimblecombe KR. et al, (2024), European Journal of Neuroscience, 59, 1242 - 1259

A fluid-walled microfluidic platform for human neuron microcircuits and directed axotomy

Nebuloni F. et al, (2024), Lab on a Chip, 24, 3252 - 3264

Multi-modal proteomic characterization of lysosomal function and proteostasis in progranulin-deficient neurons.

Hasan S. et al, (2023), Molecular neurodegeneration, 18

A fluid-walled microfluidic platform for human neuron microcircuits and directed axotomy

Nebuloni F. et al, (2023)

C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9

Vahsen BF. et al, (2023), Nature Communications, 14

Patient-derived iPSC models of Friedreich ataxia: a new frontier for understanding disease mechanisms and therapeutic application

Maheshwari S. et al, (2023), Translational Neurodegeneration, 12

Mitochondrial dysfunction and mitophagy defects in LRRK2-R1441C Parkinson’s disease models

Williamson MG. et al, (2023), Human Molecular Genetics, 32, 2808 - 2821

Impaired dopamine release in Parkinson’s disease

Cramb KML. et al, (2023), Brain, 146, 3117 - 3132

Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons

Beccano-Kelly DA. et al, (2023), iScience, 26, 107044 - 107044

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